A Rare Case of Latent Tuberculosis Reactivation Secondary to a COVID-19 Infection

Autor: Ana-Alicia Leonso, Kyle Brown, Raquel Prol, Saumya Rawat, Arjun Khunger, Romina Bromberg
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Infectious Disease Reports, Vol 14, Iss 3, Pp 446-452 (2022)
Druh dokumentu: article
ISSN: 2036-7449
DOI: 10.3390/idr14030048
Popis: Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are currently the two leading causes of death among infectious diseases. As we progress towards a “new normal”, more information is required regarding post-COVID-19 syndromes. We present a case of latent tuberculosis reactivation 3 months after a successful inpatient treatment of COVID-19. A 74-year-old female from the Philippines presented with a new left mid-lung infiltrate with worsening shortness of breath and lethargy for one week prior to admission. The clinical course of the patient deteriorated despite broad-spectrum antibiotics, diuretics, and high-dose steroid therapy requiring intubation and mechanical ventilation. Her sputum culture yielded the microbiological diagnosis of TB. Anti-tubercular medications were started and the patient had a favorable clinical outcome. Our case demonstrates that immunosuppression secondary to COVID-19 and its treatments may promote the development of an active TB infection from a latent infection. It is important to be aware of this potential increase in risk during and after a COVID-19 treatment. This is especially important in high-risk populations to ensure an early diagnosis and prompt management as well as to reduce transmission.
Databáze: Directory of Open Access Journals
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