Malignant juxtaglomerular cell tumor

Autor: Daniel Geisler, Fawaz Almutairi, Ivy John, Gabriela Quiroga-Garza, Michelle Yu, Raja Seethala, Sheldon Bastacky
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Urology Case Reports, Vol 45, Iss , Pp 102176- (2022)
Druh dokumentu: article
ISSN: 2214-4420
DOI: 10.1016/j.eucr.2022.102176
Popis: Juxtaglomerular cell tumors (JGCTs) are rare, typically benign neoplasms; only rare cases are clinically or histologically malignant. We herein report the histologic, immunophenotypic, and molecular features of a clinically unsuspected, diagnostically challenging case of malignant JGCT in a 23-year-old man. The diagnosis is confirmed with electron microscopy. The case is notable for its marked mitotic activity, which has not been previously reported in JGCTs, and novel finding of GATA3 immunohistochemical positivity.
Databáze: Directory of Open Access Journals