Autor: |
Liang-Jun Qin, Hui Xu, Li-Ping Li, Shu-Hua Li, Shuo-Yu Xu, Kai Chen, Tianyou Yang, Feng-Hua Wang, Liandong Zuo, Liang Zeng, Hai-Yun Wang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Heliyon, Vol 10, Iss 9, Pp e30901- (2024) |
Druh dokumentu: |
article |
ISSN: |
2405-8440 |
DOI: |
10.1016/j.heliyon.2024.e30901 |
Popis: |
Recent advances have revealed that the role of the immune system is prominent in the antitumor response. In the present study, it is aimed to provide an expression profile of tumor-infiltrating lymphocytes (TILs), including mature B cells, plasma cells, and their clinical relevance in neuroblastoma. The expression of CD20 and CD138 was analyzed in the Cangelosi786 dataset (n = 769) as a training dataset and in our cohort (n = 120) as a validation cohort. CD20 high expression was positively associated with favorable overall survival (OS) and event-free survival (EFS) (OS: P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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