Chronic mucocutaneous candidiasis due to signal transducer and activator of transcription 1 mutation in a Saudi patient: a case report

Autor:	Abdullah Alakeel, Khalid Nabil Nagshabandi, Abdulaziz Alsalhi
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Chronic mucocutaneous candidiasis Candida albicans signal transducer and activator of transcription 1 mutation STAT-1-GOF Dermatology RL1-803
Zdroj:	Dermatology Reports (2024)
Druh dokumentu:	article
ISSN:	2036-7392 2036-7406
DOI:	10.4081/dr.2024.9939
Popis:	Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency condition caused by a genetic abnormality that increases the risk of recurrent and persistent skin, nail and mucous membrane infections with Candida species, typically Candida albicans. Signal transducer and activator of transcription 1 (STAT 1) gene mutation is a genetic trigger that causes CMC, which increases the risk of infections, multisystem disorders and cancer susceptibility. We describe the first case of a Saudi female patient with clinical features of CMC with an underlying (STAT 1) gene mutation.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/eb28c59d9f4f4deca7ac6da73910e559 Zobrazit plný text záznamu View record in DOAJ