Imaging predictor of ophthalmic involvement in maxillary sinus cancer during super selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT)

Autor: Hirokazu Ashida, Takao Igarashi, Yosuke Nozawa, Yohei Munetomo, Takahiro Higuchi, Hideomi Yamauchi, Akira Baba, Yukiko Abe, Eiji Shimura, Hisashi Kessoku, Yukio Nishiya, Hiromi Kojima, Hiroya Ojiri
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Head & Face Medicine, Vol 17, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1746-160X
DOI: 10.1186/s13005-021-00285-z
Popis: Abstract Objective To investigate the predictability of ophthalmic artery involvement in maxillary sinus cancer using preprocedural contrast enhanced CT and MRI. Methods We analyzed advanced (T3, T4a, and T4b) primary maxillary sinus squamous cell carcinoma treated with super-selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT) from Oct 2016 to Mar 2020. Two diagnostic radiologists evaluated the tumor invasion site around the maxillary sinus using preprocedural imaging. These results were compared with the angiographic involvement of the ophthalmic artery using statistical analyses. We also evaluated our RADPLAT quality using complication rate, response to treatment, local progressive free survival (LPFS), and overall survival (OS). Results Twenty patients were included in this study. There were ten cases of ophthalmic artery tumor stain and there was a correlation between ophthalmic artery involvement and invasion for ethmoid sinus with statistically significant differences. Other imaging findings were not associated with ophthalmic artery involvement. Conclusions Ethmoid sinus invasion on preprocedural imaging could suggest ophthalmic artery involvement in maxillary sinus cancer. It may be useful in predicting prognosis and treatment selection.
Databáze: Directory of Open Access Journals
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