Association of statin use with outcomes of patients admitted with COVID-19: an analysis of electronic health records using superlearner

Autor:	Adovich S. Rivera, Omar Al-Heeti, Lucia C. Petito, Mathew J. Feinstein, Chad J. Achenbach, Janna Williams, Babafemi Taiwo
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	COVID-19 Statin Mortality Critical care Targeted maximum likelihood estimation Observational studies Infectious and parasitic diseases RC109-216
Zdroj:	BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Druh dokumentu:	article
ISSN:	1471-2334
DOI:	10.1186/s12879-023-08026-0
Popis:	Key points Question Is statin use prior to hospital admission for COVID-19 associated with reducing severe inpatient outcomes? Findings In this observational study using electronic health records from a multi-hospital health system in Chicago, we used robust statistical methods to account for confounding and found that adults 40 years or older who were prescribed statins prior to admission for COVID-19 had minimally lower rates of intubation and admission to the intensive care unit. However, inpatient mortality was comparable between statins users and non-users. Meaning Consistent with current COVID-19 treatment guidelines, we did not find evidence supporting the utilization of statins for clinically significant reduction in severe inpatient COVID-19 outcomes.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9fcbd9b911734c4f8870cd82a9f1292a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.