Comparison of the Effects of TIPS versus BRTO on Bleeding Gastric Varices: A Meta-Analysis

Autor: Zi Wen Wang, Jin Chao Liu, Fang Zhao, Wen Guang Zhang, Xu Hua Duan, Peng Fei Chen, Si Fu Yang, Hong Wei Li, Fu Wen Chen, Hong Sheng Shi, Jian Zhuang Ren
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Canadian Journal of Gastroenterology and Hepatology, Vol 2020 (2020)
Druh dokumentu: article
ISSN: 2291-2789
2291-2797
DOI: 10.1155/2020/5143013
Popis: Background and Aim. Upper gastrointestinal bleeding is a threat to patients with gastric varices (GVs). Previous studies have concluded that both transjugular intrahepatic portosystemic shunt (TIPS) and balloon-occluded retrograde transvenous obliteration (BRTO) are effective treatments for patients with GV. We aimed to compare the efficiency and outcomes of these two procedures in GV patients through meta-analysis. Methods. The PubMed, Cochrane Library, EMBASE, and Web of Science databases were searched using the keywords: GV, bleeding, TIPS, and BRTO to identify relevant randomized controlled trials and cohort studies. The overall survival (OS) rate, imminent haemostasis rate, rebleeding rate, technical success rate, procedure complication rate (hepatic encephalopathy and aggravated ascites), and Child-Pugh score were evaluated. Randomized clinical trials and cohort studies comparing TIPS and BRTO for GV due to portal hypertension were included in our meta-analysis. Two independent reviewers performed data extraction and assessed the study quality. A meta-analysis was performed to calculate risk ratios (RRs), mean differences (MDs), and 95% CIs using random effects models. Results. A total of nine studies fulfilled the inclusion criteria. There was a significant difference between TIPS and BRTO in the OS rate (RR, 0.81 (95% CI, 0.66 to 0.98); P=0.03) and rebleeding rate (RR, 2.61 (95% CI, 1.75 to 3.90); P
Databáze: Directory of Open Access Journals
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