The predictive value of the renal resistive index for contrast-induced nephropathy in patients with acute coronary syndrome

Autor: Zheng-rong Xu, Jun Chen, Yuan-hui Liu, Yong Liu, Ning Tan
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-019-1017-3
Popis: Abstract Background Percutaneous coronary intervention (PCI) has been associated with contrast-induced nephropathy (CIN) at a rate that varies depending on the patient’s risk factors. This study was conducted to evaluate the predictive value of the renal resistive index (RRI) for CIN in patients with acute coronary syndrome (ACS) undergoing PCI. Methods This prospective study enrolled 146 consecutive patients with ACS. Renal Doppler ultrasound examinations to measure RRI were performed pre-PCI and at 1 h and 24 h after PCI. The primary endpoint was CIN, defined as a relative (≥25%) or absolute (≥0.5 mg/dL; 44 μmol/L) increase in serum creatinine from baseline within 48 h after contrast exposure. Results CIN was identified in 31 patients (21.2%); however, none of the patients required haemodialysis. Compared to patients without CIN, higher RRIs were observed at 1 h (0.71 ± 0.05 vs. 0.65 ± 0.06, p
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