| Autor: |
Mahan Shafie, Elnaz Shahmohamadi, Alireza Hadizadeh, Alireza Hasanzadeh, Golsa Gholampour, Samaneh Parsa |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Cancer Reports, Vol 6, Iss 9, Pp n/a-n/a (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2573-8348 |
| DOI: |
10.1002/cnr2.1868 |
| Popis: |
Abstract Background Disseminated intravascular coagulation (DIC) has been reported in various solid malignancies and is a common coagulation‐related complication in prostate cancer. However, DIC has been rarely reported as the initial presentation of prostate cancer. Herein, we reported a patient referring with subdural hemorrhage (SDH) and DIC with an unexplained cause who was later diagnosed with prostate cancer. Case Presentation We presented a 68‐year‐old man who was referred to the hospital with a gradual deterioration of consciousness, dyspnea, and edema in the genitalia and lower limbs. His primary laboratory tests showed elevated prothrombin time (PT) and partial thromboplastin time (PTT) and a decreased fibrinogen level of 47 mg/dL [200–400 mg/dL]. The DIC score was 7, which was suggestive of DIC. Moreover, cranial imaging showed SDH. Further work‐up revealed elevated prostate‐specific antigen and prostate enlargement with a mass effect on the bladder with a bone lesion, which was suggestive of metastatic prostate cancer. Conclusion This report highlights DIC as a possible initial presentation of an underlying malignancy, as well as the importance of treatment of underlying disease in the management of DIC. A comprehensive and systematic work‐up is essential for early diagnosis in patients with DIC to avoid further complications and mortality. |
| Databáze: |
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