Evolution of genetic redundancy: the relevance of complexity in genotype–phenotype mapping

Autor: Nen Saito, Shuji Ishihara, Kunihiko Kaneko
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: New Journal of Physics, Vol 16, Iss 6, p 063013 (2014)
Druh dokumentu: article
ISSN: 1367-2630
DOI: 10.1088/1367-2630/16/6/063013
Popis: Despite its ubiquity among organisms, genetic redundancy is presumed to reduce total population fitness and is therefore unlikely to evolve. This study evaluates an evolutionary model with high-dimensional genotype–phenotype mapping (GPM) by applying a replica method to deal with quenched randomness. From the method, the dependence of fitness on genetic redundancy is analytically calculated. The results demonstrate that genetic redundancy can have higher population fitness under complex GPM, which tends to favor gene duplication in selection processes, further enhancing the potential for evolutionary innovations.
Databáze: Directory of Open Access Journals