Echocardiographic alterations in a child with cow’s milk allergy: a case report

Autor: Di Cara Giuseppe, Berioli Maria, Biscarini Anna, Soldani Claudia, Abate Piera, Ugolini Eleonora, Allocca Giusiana, Milioni Maddalena
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 6, Iss 1, p 299 (2012)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/1752-1947-6-299
Popis: Abstract Introduction Cow’s milk allergy is the most frequent food allergy in Europe and western countries and shows a wide spectrum of clinical features, including atopic dermatitis and gastrointestinal disease. To the best of our knowledge, this report is the first to describe Kawasaki disease-like clinical features and echocardiographic alterations which resolved after a cow’s milk-free diet. Case presentation We report a case of a 9-month-old Caucasian girl with atopic dermatitis who developed clinical features commonly present in Kawasaki disease (erythematous skin rash, non-exudative conjunctivitis, fissured lips and neck lymph nodes), together with mild echocardiographic alterations (perivascular brightness, pericardial effusion) in the absence of fever. These features resolved within 2 weeks after the beginning of a cow’s milk-free diet. Conclusion Kawasaki disease has recently been considered a possible risk factor for subsequent allergic disease secondary to immune dysfunction. This case report suggests that the immune-related alterations which are commonly present in allergic patients could be similar to the antigen-related immune response in Kawasaki disease and thus could lead to similar clinical features.
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