Application of β-Glucosidase in a Biphasic System for the Efficient Conversion of Polydatin to Resveratrol

Autor:	Jie Zhou, Meng Liang, Yu Lin, Hao Pang, Yutuo Wei, Ribo Huang, Liqin Du
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	resveratrol polydatin β-D-Glucosidase biphasic enzymatic transformation Organic chemistry QD241-441
Zdroj:	Molecules, Vol 27, Iss 5, p 1514 (2022)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules27051514
Popis:	Resveratrol, an ingredient of traditional Chinese medicine, has beneficial effects on human health and huge potential for application in modern medicine. Polydatin is extracted from plants and then deglycosylated into resveratrol; enzymatic methods are preferred for this reaction. In this study, a β-D-glucosidase from Sphingomonas showed high efficiency in transforming polydatin into resveratrol and was tolerant toward organic solvents. Applying this enzyme in a biphasic transformation system resulted in 95.3% conversion of 20% concentration crude polydatin to resveratrol in 4 h. We thus report a new method for high-efficiency, clean production of resveratrol.
Databáze:	Directory of Open Access Journals
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