Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy

Autor: Lucas M Bachmann, Konstantinos Balaskas, Gavin Tan, Dawn A Sim, Peter B M Thomas, Meriam Islam, Stafford Sansome, Radha Das, Marko Lukic, Kelvin Yi Chong Teo, Andrew M Schimel
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMJ Health & Care Informatics, Vol 28, Iss 1 (2021)
Druh dokumentu: article
ISSN: 2632-1009
DOI: 10.1136/bmjhci-2020-100310
Popis: Background/aims To assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy.Design Observational study with retrospective analysis of data.Methods Participants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person or by using video and telephone consultations. Automated threshold-based alerts were communicated based on a traffic light system. A ‘threshold alarm’ was defined as three consecutive ‘red’ scores, and turned into a ‘persistent alarm’ if present for greater than a 7-day period. Changes of VA and CMT, and the requirement for intravitreal therapy after an alarm were examined.Results 245 patients performing a total of 11 592 tests (mean 46.9 tests per user) were included and 85 eyes (164 alarms) examined. Mean drop in VA from baseline was −4.23 letters (95% CI: −6.24 to −2.22; p
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