Characteristics of insulin-Naïve people with type 2 diabetes who successfully respond to insulin glargine U100 after 24 weeks of treatment: a meta-analysis of individual participant data from 3 randomized clinical trials

Autor: M. H. Cummings, D. Cao, I. Hadjiyianni, L. L. Ilag, M. H. Tan
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Clinical Diabetes and Endocrinology, Vol 4, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 2055-8260
DOI: 10.1186/s40842-018-0059-2
Popis: Abstract Background To identify baseline/clinical characteristics associated with clinically meaningful responses to insulin glargine 100 U/mL (IGlar) in insulin-naive people with type 2 diabetes mellitus (T2DM). Methods Individual participant data were pooled from 3 randomized trials to compare baseline characteristics and clinical outcomes associated with 24-week response to IGlar in combination with non-insulin antihyperglycemic agents in participants with T2DM. Responders were defined as achieving endpoint HbA1c target
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