Tophi reduction: ultrasound imaging and correlation with plasma levels of uric acid in patients undergoing treatment for tophaceous gout

Autor: A.J.L. Ferrari, A.R. Corrêa Fernandes, R. de Almeida Agustinelli, H. Seike, E. de Ávila Fernandes
Jazyk: English<br />Italian
Rok vydání: 2019
Předmět:
Zdroj: Reumatismo, Vol 71, Iss 2 (2019)
Druh dokumentu: article
ISSN: 0048-7449
2240-2683
DOI: 10.4081/reumatismo.2019.1058
Popis: The objective was to determine the reduction of tophi in patients undergoing drug therapy in correlation with urate serum levels through ultrasound examination. A total of 31 male patients, between the ages of 33 to 77 years, with tophaceous gout were evaluated between 2005 and 2009, 11 of which were selected. Ultrasound examinations of visible tophi and evaluations of serum uric acids levels were performed annually on each patient. There was a statistically significant difference between measurements 1, 2, 3 and measurement 4 and between measurements 4 and 5. A strong significant positive association was seen between variation of tophus size and the reduction of serum uric acid levels.
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