The Role of Predictability in Saccadic Eye Responses in the Suppression Head Impulse Test of Horizontal Semicircular Canal Function
| Autor: | Jorge Rey-Martinez, Joaquin Yanes, Jonathan Esteban, Ricardo Sanz, Eduardo Martin-Sanz |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Frontiers in Neurology, Vol 8 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1664-2295 34631143 |
| DOI: | 10.3389/fneur.2017.00536 |
| Popis: | BackgroundIn the suppression head impulse paradigm (SHIMP) vHIT protocol, the participant is instructed to follow with his gaze a mobile target generated by a laser placed on the participant’s head. Recent studies have reported that the refixation saccade latencies are in relation with the time evolution of the vestibular dysfunction in both (standard and SHIMP) procedures. We hypothesized that some central mechanisms like head impulse prediction could be one of the causes for the differences in the saccadic eye responses.MethodsA prospective cohort non-randomized study was designed. For the SHIMP protocol, recorded with the ICS Impulse ver. 4.0® (Otometrics A/S, Taastrup, Denmark) vHIT device, three different algorithms were performed: “predictable,” “less predictable,” and “unpredictable” depending on the target’s predictability. A mathematical method was developed to analyze the SHIMP responses. The method was implemented as an additional tool to the MATLAB open source script for the extended analysis of the vHIT responses named HITCal.ResultsIn cohort 1, 52 participants were included in “predictable” SHIMP protocol. In cohort 2, 60 patients were included for the “less predictable” and 35 patients for the “unpredictable” SHIMP protocol. The participants made more early saccades when instructed to perform the “predictable” paradigm compared with the “less predictable” paradigm (p |
| Databáze: | Directory of Open Access Journals |
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