| Autor: |
Jan Hofmaier, Raphael Bodensohn, Sylvia Garny, Indrawati Hadi, Daniel F. Fleischmann, Michael Eder, Yavuz Dinc, Michael Reiner, Stefanie Corradini, Katia Parodi, Claus Belka, Maximilian Niyazi |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Radiation Oncology, Vol 14, Iss 1, Pp 1-8 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1748-717X |
| DOI: |
10.1186/s13014-019-1315-z |
| Popis: |
Abstract Background In this dosimetric study, a dedicated planning tool for single isocenter stereotactic radiosurgery for multiple brain metastases using dynamic conformal arc therapy (DCAT) was compared to standard volumetric modulated arc therapy (VMAT). Methods Twenty patients with a total of 66 lesions who were treated with the DCAT tool were included in this study. Single fraction doses of 15–20 Gy were prescribed to each lesion. Patients were re-planned using non-coplanar VMAT. Number of monitor units as well as V4Gy, V5Gy and V8Gy were extracted for every plan. Using a density-based clustering algorithm, V10Gy and V12Gy and the volume receiving half of the prescribed dose were extracted for every lesion. Gradient indices and conformity indices were calculated. The correlation of the target sphericity, a measure of how closely the shape of the target PTV resembles a sphere, to the difference in V10Gy and V12Gy between the two techniques was assessed using Spearman’s correlation coefficient. Results The automated DCAT planning tool performed significantly better in terms of all investigated metrics (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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