Free Prostate-Specific Antigen Provides More Precise Data on Benign Prostate Volume Than Total Prostate-Specific Antigen in Korean Population

Autor: Hoon Choi, Jae Young Park, Ji Sung Shim, Jae Heon Kim, Jae Hyun Bae
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: International Neurourology Journal, Vol 17, Iss 2, Pp 73-77 (2013)
Druh dokumentu: article
ISSN: 2093-4777
2093-6931
DOI: 10.5213/inj.2013.17.2.73
Popis: Purpose: To investigate the efficacy of total prostate-specific antigen (tPSA) and free prostate-specific antigen (fPSA) for the estimation of prostate volume (PV) in pathologically-proven benign prostatic hyperplasia (BPH) patients. Methods: From January 2010 to March 2013, 165 Korean men with a PSA less than 10 ng/mL who were diagnosed without prostate cancer by prostate biopsy were enrolled. Patients were classified into three age groups: ≤60, 61–70, and >70 years old. The results were organized to estimate and compare the ability of serum tPSA and fPSA to assess the PV. Results: Enrolled patients had a median age of 63.5 years (44 to 80), a median tPSA of 5.72 ng/mL, a median fPSA of 0.98 ng/mL and a median PV of 53.68 mL, respectively. Among the associations between tPSA, fPSA, age, and PV, the highest correlation was verified between fPSA and PV (r=0.377, P
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