| Autor: |
Gabriella Kervefors, Antonia Becker, Chandan Dey, Berit Olofsson |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1491-1497 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.14.126 |
| Popis: |
A transition metal-free formal synthesis of phenoxazine is presented. The key step of the sequence is a high-yielding O-arylation of a phenol with an unsymmetrical diaryliodonium salt to provide an ortho-disubstituted diaryl ether. This species was cyclized to acetylphenoxazine in moderate yield. The overall yield in the three-step sequence is 72% based on recovered diaryl ether. An interesting, unusually stable iodine(III) intermediate in the O-arylation was observed by NMR and could be converted to the product upon longer reaction time. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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