Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Autor: Mathias Rask-Andersen, Torgny Karlsson, Weronica E. Ek, Åsa Johansson
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-08000-4
Popis: Obesity and the distribution of fat within the body are risk factors for cardiometabolic diseases. Here, Rask-Andersen et al. perform GWAS for bio-electrical impedance measurements in UK Biobank participants and identify 29 novel independent loci for fat distribution and a high degree of sex-heterogeneity.
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