The Role of Spongia sp. in the Discovery of Marine Lead Compounds

Autor: Patrícia Máximo, Luísa M. Ferreira, Paula Branco, Pedro Lima, Ana Lourenço
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Marine Drugs, Vol 14, Iss 8, p 139 (2016)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md14080139
Popis: A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterterpenes, sterols (including secosterols), macrolides and miscellaneous compounds. Among other reports we include studies on the intraspecific diversity of a Mediterranean species, compounds isolated from associated sponge and nudibranch and compounds isolated from S. zimocca and the red seaweed Laurentia microcladia. Under biological activity a table of the reported biological activities of the various compounds and the biological screening of extracts are described. The present review covers the literature from 1971 to 2015.
Databáze: Directory of Open Access Journals