Mechanical thrombectomy with combined stent retriever and contact aspiration versus stent retriever alone for acute large vessel occlusion: data from ANGEL-ACT registry

Autor: Ning Ma, Xiangqun Shi, Lianbo Gao, Yajie Liu, Yongli Li, Dapeng Mo, Feng Gao, Zhongrong Miao, Yan Liu, Zengwu Wang, Yan Wang, Wei Wang, Weihua Wu, Liping Wei, Ping Xu, Jianfeng Zhou, Hao Li, Lei Yang, Yang Hua, Xiaochuan Huo, Ya Peng, Wenhuo Chen, Shengli Chen, Cunfeng Song, Ping Jing, Junfeng Zhao, Liqiang Gui, Zhiming Zhou, Anxin Wang, Zhimin Wang, Yibin Cao, Hongwei Wang, Dong Wang, Peng Zhang, Zhonghua Shi, Haitao Guan, Chao Wang, Long Chen, Xue Wen, Wei Dong, Hui Liang, Chunlei Li, Qingfeng Zhu, Jun Wei, Yun Xu, Xiang Luo, Jin Wu, Zhi Yang, Yongqiang Zhang, Baixue Jia, Yaxuan Sun, Guilian Zhang, Gang Xie, Chong Li, Yuwu Zhao, Wang Bo, Shugui Shi, Yan Xiao, Xiaoxiang Peng, Zaiyu Guo, Ning Guan, Haihua Yang, Gaoting Ma, Xu Tong, Guangxiong Yuan, Deqin Geng, Dapeng Sun, Raynald, Leyuan Wang, Yijiu Lu, Xianjun Wang, Zhenzhong Zhang, Shijun Zhao, Qingshi Zhao, Qingchun Gao, Weirong Li, Xiaojiang Cheng, Xinyu Lu, Dengxiang Wang, Haicheng Yuan, Xuancong Liufu, Wenwu Yang, Wenji Jing, WenWu Peng, Lixin Wang, Wanming Wang, Pu Yuan, Wenbao Liang, Daliang Ma, Xiangdong Xie, Xiangjun Zeng, Fanfan Su, MingZe Chang, Jijun Yin, Hongxia Sun, Yong Bi, Dongqun Li, Zhonglun Chen, Lin Yin, HongKai Qiu, Xiaoya Feng, Tan Lan, Qilong Liang Li Ding, Jianwen Yang, Quanle Zheng, Zhenyun Zhu, Liyue Zhao, Qingbo Meng, Yuqing Wei, Dong Sun, Yongxing Yan, Yadong Yang, Huihong Wang, Xianglin Chen, Juntao Li, Xiang Yong, Mingkai Hu, Yu Xin Wang
Jazyk: angličtina
Předmět:
Zdroj: Stroke and Vascular Neurology, Vol , Iss
Druh dokumentu: article
ISSN: 2059-8696
DOI: 10.1136/svn-2022-001765
Popis: Background and purpose An analysis of the ASTER 2 trial revealed similar final recanalisation levels and clinical outcomes in acute large vessel occlusion (LVO) stroke between stent retrieval (SR) alone as a first-line mechanical thrombectomy (MT) technique (SR alone first-line) and concomitant use of contact aspiration (CA) plus SR as a first-line MT technique (SR+CA first-line). The purpose of the present study was to compare the safety and efficacy of SR+CA first-line with those of SR alone first-line for patients with LVO in China.Methods We conducted the present study by using the data from the ANGEL-ACT registry. We divided the selected patients into SR+CA first-line and SR alone first-line groups. We performed logistic regression and generalised linear models with adjustments to compare the angiographic and clinical outcomes, including successful/complete recanalisation after the first technique alone and all procedures, first-pass successful/complete recanalisation, number of passes, 90-day modified Rankin Scale, procedure duration, rescue treatment and intracranial haemorrhage within 24 hours.Results Of the 1233 enrolled patients, 1069 (86.7%) received SR alone first-line, and 164 (13.3%) received SR+CA first-line. SR+CA first-line was associated with more thrombectomy passes (3 (2–4) vs 2 (1–2); β=1.77, 95% CI=1.55 to 1.99, p0.05) between the two groups.Conclusions Patients undergoing SR+CA first-line had more thrombectomy passes and longer procedure duration than patients undergoing SR alone first-line. Additionally, we suggested that SR+CA first-line was not superior to SR alone first-line in final recanalisation level, first-pass recanalisation level and 90-day clinical outcomes in the Chinese population.
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