| Autor: |
Robert C. Kaplan, Rebecca J. Song, Juan Lin, Vanessa Xanthakis, Simin Hua, Ariel Chernofsky, Kelly R. Evenson, Maura E. Walker, Carmen Cuthbertson, Joanne M. Murabito, Christina Cordero, Martha Daviglus, Krista M. Perreira, Marc Gellman, Daniela Sotres-Alvarez, Ramachandran S. Vasan, Xiaonan Xue, Nicole L. Spartano, Yasmin Mossavar-Rahmani |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
BMC Public Health, Vol 22, Iss 1, Pp 1-11 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2458 |
| DOI: |
10.1186/s12889-022-13463-8 |
| Popis: |
Abstract Background Non-genetic factors contribute to differences in diabetes risk across race/ethnic and socioeconomic groups, which raises the question of whether effects of predictors of diabetes are similar across populations. We studied diabetes incidence in the primarily non-Hispanic White Framingham Heart Study (FHS, N = 4066) and the urban, largely immigrant Hispanic Community Health Study/Study of Latinos (HCHS/SOL, N = 6891) Please check if the affiliations are captured and presented correctly. Methods Clinical, behavioral, and socioeconomic characteristics were collected at in-person examinations followed by seven-day accelerometry. Among individuals without diabetes, Cox proportional hazards regression models (both age- and sex-adjusted, and then multivariable-adjusted for all candidate predictors) identified predictors of incident diabetes over a decade of follow-up, defined using clinical history or laboratory assessments. Results Four independent predictors were shared between FHS and HCHS/SOL. In each cohort, the multivariable-adjusted hazard of diabetes increased by approximately 50% for every ten-year increment of age and every five-unit increment of body mass index (BMI), and was 50–70% higher among hypertensive than among non-hypertensive individuals (all P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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