In Vitro Evaluation of the Activity of Aztreonam-Avibactam against 341 Recent Clinical Isolates of Anaerobes

Autor: David R. Snydman, Laura McDermott
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Microbiology Spectrum, Vol 9, Iss 3 (2021)
Druh dokumentu: article
ISSN: 2165-0497
DOI: 10.1128/Spectrum.01908-21
Popis: ABSTRACT Aztreonam-avibactam is under clinical development for multidrug-resistant Gram-negative infections. We evaluated in vitro activity against 341 recent clinical isolates. The addition of avibactam to aztreonam had no effect on the anaerobic activity of aztreonam. IMPORTANCE This work shows that aztreonam-avibactam lacks activity against anaerobic organisms.
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