Timing It Right: Endoscopic Necrosectomy for Infected Necrotizing Pancreatitis

Autor:	Ashutosh Ishan Yadav, Surinder Singh Rana
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	pancreatitis lumen-apposing metal stent necrosectomy Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Journal of Digestive Endoscopy, Vol 15, Iss 02, Pp 153-156 (2024)
Druh dokumentu:	article
ISSN:	0976-5042 0976-5050
DOI:	10.1055/s-0044-1782232
Popis:	The endoscopic step-up drainage approach involving initial drainage followed by, if required, direct endoscopic necrosectomy (DEN) is the preferred management approach for symptomatic pancreatic necrotic collections. However, limited data suggests that immediate DEN during initial stent placement may hasten clinical recovery by quicker resolution of systemic inflammatory response. However, because of concerns about adverse effects, especially gastric perforation and bleeding, most endoscopists prefer delayed DEN. In this news and views, we discuss a recently published randomized controlled trial that compared upfront necrosectomy at the index intervention versus as a step-up for patients with infected necrotizing pancreatitis.
Databáze:	Directory of Open Access Journals
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