The rapid and efficient strategy for SARS-CoV-2 Omicron transmission control: analysis of outbreaks at the city level

Autor: Jin-Xin Zheng, Shan Lv, Li-Guang Tian, Zhao-Yu Guo, Pei-Yong Zheng, Yue-Lai Chen, Shi-Yang Guan, Wei-Ming Wang, Shun-Xian Zhang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Infectious Diseases of Poverty, Vol 11, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2049-9957
DOI: 10.1186/s40249-022-01043-2
Popis: Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant is highly transmissible with potential immune escape. Hence, control measures are continuously being optimized to guard against large-scale coronavirus disease 2019 (COVID-19) outbreaks. This study aimed to explore the relationship between the intensity of control measures in response to different SARS-CoV-2 variants and the degree of outbreak control at city level. Methods A retrospective study was conducted in 49 cities with COVID-19 outbreaks between January 2020 and June 2022. Epidemiological data on COVID-19 were extracted from the National Health Commission, People’s Republic of China, and the population flow data were sourced from the Baidu migration data provided by the Baidu platform. Outbreak control was quantified by calculating the degree of infection growth and the time-varying reproduction number ( $${R}_{t}$$ R t ). The intensity of the outbreak response was quantified by calculating the reduction in population mobility during the outbreak period. Correlation and regression analyses of the intensity of the control measures and the degree of outbreak control for the Omicron variant and non-Omicron mutants were conducted, respectively. Results Overall, 65 outbreaks occurred in 49 cities in China from January 2020 to June 2022. Of them, 66.2% were Omicron outbreaks and 33.8% were non-Omicron outbreaks. The intensity of the control measures was positively correlated with the degree of outbreak control (r = 0.351, P = 0.03). The degree of reduction in population mobility was negatively correlated with the R t value (r = − 0.612, P
Databáze: Directory of Open Access Journals
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