| Autor: |
ZHANG Hui, WANG Jianhong, WANG Shuxian, FENG Shuai, LIU Jinquan, XU Xiangmei, DAI Deshu, SUN Shuang, XU Chuanshen |
| Jazyk: |
čínština |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
精准医学杂志, Vol 39, Iss 1, Pp 71-73 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2096-529X |
| DOI: |
10.13362/j.jpmed.202401018 |
| Popis: |
Objective To investigate the clinical efficacy of domino liver transplantation (DLT) and to provide a refe-rence for expanding the sources of donor livers. Methods The clinical data of two cases who underwent DLT at our hospital in 2021 were collected, and a literature review was performed. Results Donor 1 was a healthy subject, recipient 1 (DLT donor) was a patient with ornithine transcarbamylase deficiency, and recipient 2 (DLT recipient) was a patient with Cirgler-Najiar syndrome. Donor 2 was a brain-dead donor as per the internationally standardized definitions, recipient 3 (DLT donor) was a patient with familial hypercholesterolemia, and recipient 4 (DLT recipient) was a patient with malignant liver tumor. After transplantation, all patients experienced recovery of their liver function in 1 week, and were discharged from the hospital after 2 to 4 weeks of hospitalization. Recipient 2 developed thrombosis in the left portal vein on day 4 after operation; after emergent thrombolysis and anticoagulant therapy, the blood flow of the portal vein was effectively improved, and no serious outcomes were identified; the bilirubin level of the patient returned to normal at 1 week after operation. Recipient 4 developed hyperlipidemia after operation and was treated with atorvastatin and ezetimibe for lipid regulation; the patient was followed up till now with no additional complications found. Conclusion DLT can effectively expand the sources of donor livers. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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