Autor: |
Saksham Tripathi, Saad Tarabichi, Javad Parvizi, Ashok Rajgopal |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
Arthroplasty, Vol 5, Iss 1, Pp 1-10 (2023) |
Druh dokumentu: |
article |
ISSN: |
2524-7948 |
DOI: |
10.1186/s42836-023-00192-5 |
Popis: |
Abstract With a significant rise in the number of arthroplasty procedures performed worldwide, the increasing revision burden posed by periprosthetic joint infection (PJI) is a matter of growing concern. In spite of various attempts to diagnose PJI, there are no defined tests that can be called a gold standard. Given the importance of early diagnosis in PJI, newer tests and biomarkers have been introduced to improve cumulative diagnostic accuracy. Novel biomarkers like calprotectin, lipocalcin, monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and platelet-to-mean platelet volume ratio have demonstrated a potential as diagnostic biomarkers for PJI. This article discusses the relevance of available and newly described diagnostic biomarkers to provide a perspective on the practical applicability in current medical practice, as well as highlights some recent advances in biomarkers for the diagnosis of PJI. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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