P-wave duration and interatrial block as predictors of new-onset atrial fibrillation: A systematic review and meta-analysis

Autor: Konstantinos Zagoridis, Emmanuel Koutalas, Stergios Intzes, Marianthi Symeonidou, Nikoleta Zagoridou, Konstantinos Karagogos, Emmanuel Spanoudakis, Emmanuel Kanoupakis, George Kochiadakis, Borislav Dinov, Nikolaos Dagres, Gerhard Hindricks, Andreas Bollmann, Sotirios Nedios
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Hellenic Journal of Cardiology, Vol 72, Iss , Pp 57-64 (2023)
Druh dokumentu: article
ISSN: 1109-9666
DOI: 10.1016/j.hjc.2023.03.007
Popis: Background: Early detection of atrial fibrillation (AF) could improve patient outcomes. P-wave duration (PWD) and interatrial block (IAB) are known predictors of new-onset AF and could improve selection for AF screening. This meta-analysis reviews the published evidence and offers practical implications. Methods: Publication databases were systematically searched, and studies reporting PWD and/or morphology at baseline and new-onset AF during follow-up were included. IAB was defined as partial (pIAB) if PWD≥120 ms or advanced (aIAB) if the P-wave was biphasic in the inferior leads. After quality assessment and data extraction, random-effects analysis calculated odds ratio (OR) and confidence intervals (CI). Subgroup analysis was performed for those with implantable devices (continuous monitoring). Results: Among 16,830 patients (13 studies, mean 66 years old), 2,521 (15%) had new-onset AF over a median of 44 months. New-onset AF was associated with a longer PWD (mean pooled difference: 11.5 ms, 13 studies, p
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