The complete structure of an activated open sodium channel

Autor: Altin Sula, Jennifer Booker, Leo C. T. Ng, Claire E. Naylor, Paul G. DeCaen, B. A. Wallace
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms14205
Popis: Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.
Databáze: Directory of Open Access Journals