Vitamin D deficiency in patients with retinal vein occlusion: a systematic review and meta-analysis

Autor: Kimia Daneshvar, Mohammadreza Akhlaghi, Shila Iranpour, Matin Irajpour, Mohsen Pourazizi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Retina and Vitreous, Vol 10, Iss 1, Pp 1-9 (2024)
Druh dokumentu: article
ISSN: 2056-9920
DOI: 10.1186/s40942-024-00571-3
Popis: Abstract Background This review aims to substantiate the correlation between vitamin D and retinal vein occlusion (RVO) within the medical literature. Method A systematic review and meta-analysis were conducted in PubMed, SCOPUS, Web of Science, and Embase until December 10th, 2023. A meticulous literature search was undertaken to identify and analyze all observational-analytical papers reporting vitamin D levels in RVO patients. The principal outcome measures centered on the comparative assessment of vitamin D levels between patients with RVO (cases) and those devoid of RVO (controls). The protocol was registered in PROSPERO (code: CRD42024499853). Results A total of six relevant studies consisting of 589 participants were included in this meta-analysis. The results indicated a significant association between vitamin D deficiency and increased risk of RVO (Odds ratio = 14.51; 95% CI: [1.71, 122.59], P = 0.014); and patients with RVO exhibited a significant decrease in serum vitamin D levels by 1.91ng/mL (95% CI: [-2.29, -1.54], P
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