The Role of Adipokines in Health and Disease

Autor: Vicente Javier Clemente-Suárez, Laura Redondo-Flórez, Ana Isabel Beltrán-Velasco, Alexandra Martín-Rodríguez, Ismael Martínez-Guardado, Eduardo Navarro-Jiménez, Carmen Cecilia Laborde-Cárdenas, José Francisco Tornero-Aguilera
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biomedicines, Vol 11, Iss 5, p 1290 (2023)
Druh dokumentu: article
ISSN: 2227-9059
DOI: 10.3390/biomedicines11051290
Popis: Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a low-grade state of inflammation and different pathologies. The present review aims to analyze the role of adipokines in health and disease in order to understand the important functions and effects of these cytokines. For this aim, the present review delves into the type of adipocytes and the cytokines produced, as well as their functions; the relations of adipokines in inflammation and different diseases such as cardiovascular, atherosclerosis, mental diseases, metabolic disorders, cancer, and eating behaviors; and finally, the role of microbiota, nutrition, and physical activity in adipokines is discussed. This information would allow for a better understanding of these important cytokines and their effects on body organisms.
Databáze: Directory of Open Access Journals