State or trait: the neurobiology of anorexia nervosa — contributions of a functional magnetic resonance imaging study

Autor: Selma Göller, Kathrin Nickel, Isabelle Horster, Dominique Endres, Almut Zeeck, Katharina Domschke, Claas Lahmann, Ludger Tebartz van Elst, Simon Maier, Andreas A. B. Joos
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Eating Disorders, Vol 10, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2050-2974
DOI: 10.1186/s40337-022-00598-7
Popis: Plain English summary There is abundant evidence of structural and functional brain alterations during the acute stage of anorexia nervosa (AN), although affected brain areas differ based on various study methodologies. Meanwhile, investigations indicate that brain structure normalizes with weight and clinical restitution. The current cross-sectional investigation examines acutely ill AN patients, healthy controls, i.e. non-patients (NP) and well-recovered individuals (REC), with respect to brain function. Functional cerebral responses of participants exposed to food pictures were investigated. Neither in terms of function nor emotional experience of food stimuli, the REC differed from the NP group. This study points to brain function normalizing with clinical and weight restoration, which should be verified in intra-individual longitudinal studies.
Databáze: Directory of Open Access Journals
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