Tolerance and efficacy of HIFU ablation for uterine fibroids NPVR ≥ 90%: a nested case-control study
| Autor: | Xue Gong, Dang Liu, Mei-Jie Yang, Rong Zhang, Wen-Zhi Chen, Jin-Yun Chen |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International Journal of Hyperthermia, Vol 39, Iss 1, Pp 946-951 (2022) |
| Druh dokumentu: | article |
| ISSN: | 02656736 1464-5157 0265-6736 |
| DOI: | 10.1080/02656736.2022.2093414 |
| Popis: | Objective To investigate the tolerance and efficacy of HIFU ablation for uterine fibroids with a non-perfused volume ratio (NPVR) ≥ 90%.Methods A prospective cohort study of 2411 patients from 20 clinical centers was available. Contrast-enhanced MRI was used to assess the non-perfused volume ratio (NPVR). The International Society of Interventional Radiotherapy (SIR) complication grading system was used as the tolerance index. Uterine Fibroids-related Symptoms-Quality of Life (UFS-QoL) was used to evaluate the efficacy.Results A total of 1352 patients underwent USgHIFU ablation treatment enrolled, NPVR was median 91.9% (IQR, 81.4%,100.0%). There was 761 case (56.3%) in the NPVR ≥ 90% group in which 17.5% case experienced SIR-B abdominal pain, 591 cases (43.7%) in NPVR < 90% group in which 9.3% case had SIR-B abdominal pain. There were statistically differences in the improvement degree of UFS at 12 months among the four subgroups (NPVR < 70%, 70%–80%, 80%–90%, 90%–100%) (all p |
| Databáze: | Directory of Open Access Journals |
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