| Autor: |
Keiko Nobukuni, Kazuhiro Shirozu, Aiko Maeda, Kouta Funakoshi, Midoriko Higashi, Ken Yamaura |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
JA Clinical Reports, Vol 9, Iss 1, Pp 1-7 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2363-9024 |
| DOI: |
10.1186/s40981-023-00635-7 |
| Popis: |
Abstract Purpose Remimazolam, a newly developed ultra-short-acting benzodiazepine, provides early recovery of consciousness but its effects on memory recovery are unclear. This study examined memory recovery after emergence from general anesthesia using remimazolam. Methods Seventy-four patients undergoing breast surgery between October 2021 and March 2022 were enrolled and randomly assigned to receive propofol (control group) or remimazolam as general anesthetic during surgery. The primary endpoint was the number of posters patients remembered 24 h after surgery (among four posters shown after recovering from anesthesia) as an assessment of memory retention. The secondary endpoints were the recall of a numeric character patients had been shown just before anesthetic induction, as an assessment of retrograde amnesia 24 h after surgery. Results Sixty-six patients (propofol, 32; remimazolam, 34) were assessed. Patients in the remimazolam group remembered significantly fewer posters shown to them after surgery than those in the propofol group (0 [0 − 2] vs. 2 [1 − 3], p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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