The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine
| Autor: | Nevešćanin Marina M., Avramov-Ivić Milka L., Petrović Slobodan D., Mijin Dušan Ž., Banović-Stević Sonja N., Jovanović Vladislava M. |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Journal of the Serbian Chemical Society, Vol 78, Iss 9, Pp 1373-1385 (2013) |
| Druh dokumentu: | article |
| ISSN: | 0352-5139 38926237 |
| DOI: | 10.2298/JSC121228032N |
| Popis: | The catalytic abilities of gold electrode were tested for the quantitative determination of amphetamine (A) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) standards by their oxidation using cyclic voltammetry (CV). The value of the oxidative currents of A and MDMA standards at 0.80 V vs. SCE in 0.05 M NaHCO3 at the scan rate of 50 mV/s is linear function of concentration in range of 110.9-258.9 mM and 38.7-229.2 mM, respectively. Square wave voltammetry (SWV) revealed linear increase of current with concentration of MDMA (range 30.9-91.6 mM) and thus quantitative determination of amphetamine derivates. SWV analysis is successfully performed in spiked urine samples as well. A and MDMA in the presence of sucrose and as a content in illegally produced tablets were also analyzed. The voltammetric determination of A and MDMA derivatives using CV and SWV at gold electrode is a rapid, selective and simple procedure and its accuracy was confirmed with reference method, high performance liquid chromatography (HPLC). The spiked urine samples analysis offers additional possibility for the rapid detection of A and MDMA in human urine. |
| Databáze: | Directory of Open Access Journals |
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