Recommendations for the measurement of sexual steroids in clinical practice. A position statement of SEQCML/SEEN/SEEP

Autor: Casals Gregori, Costa Roser Ferrer, Rull Eulàlia Urgell, Escobar-Morreale Héctor F., Argente Jesús, Sesmilo Gemma, Biagetti Betina
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2023
Předmět:
Zdroj: Advances in Laboratory Medicine, Vol 4, Iss 1, Pp 52-60 (2023)
Druh dokumentu: article
ISSN: 2628-491X
DOI: 10.1515/almed-2023-0020
Popis: The proper clinical approach to a wide range of disorders relies on the availability of accurate, reproducible laboratory results for sexual steroids measured using methods with a high specificity and sensitivity. The chemiluminescent immunoassays currently available have analytical limitations with significant clinical implications. This position statement reviews the current limitations of laboratory techniques for the measurement of estradiol and testosterone and their impact on diverse clinical scenarios. A set of recommendations are provided to incorporate steroid hormone analysis by mass spectrometry in national health systems. International societies have recommended this methodology for a decade.
Databáze: Directory of Open Access Journals