| Autor: |
Onur Erdogan, Ekrem Karaayvaz, Tugba Erdogan, Cafer Panc, Remzi Sarıkaya, Aytac Oncul, Ahmet Kaya Bilge |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Revista Portuguesa de Cardiologia, Vol 40, Iss 11, Pp 829-835 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0870-2551 |
| DOI: |
10.1016/j.repc.2020.12.013 |
| Popis: |
Introduction: Ventricular arrhythmias are caused by scar tissue in patients with ischemic dilated cardiomyopathy. The gold standard imaging technique for detecting scar tissue is magnetic resonance imaging (MRI). However, MRI is not feasible for use as a screening test, and also cannot be used in patients who have received an implantable cardioverter-defibrillator (ICD). In this study, we aimed to assess the association between levels of galectin-3 (Gal-3), which is known to be secreted by scar tissue, and the history of ventricular arrhythmias in patients with ischemic dilated cardiomyopathy who received an ICD. Methods: Nineteen healthy controls and 32 patients who had previously undergone VVI-ICD implantation due to ischemic dilated cardiomyopathy were enrolled in the study. Patients were divided into three groups: the first group including patients who had received no ICD therapies, the second including patients with arrhythmia requiring therapies with no arrhythmia storm, and the third including patients who had arrhythmia storm. We assessed the association between Gal-3 levels and the history of ventricular arrhythmias in these patients. Results: Gal-3 levels were significantly higher in the patient groups than in the control group (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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