Correlation of vascular endothelial growth factor with the clinical regression of tubercular granuloma
Autor: | Manisha Agarwal, Chanda Gupta, K Varsha Mohan, Pramod K Upadhyay, Vivek Jha |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Indian Journal of Ophthalmology, Vol 68, Iss 9, Pp 2037-2040 (2020) |
Druh dokumentu: | article |
ISSN: | 0301-4738 1998-3689 |
DOI: | 10.4103/ijo.IJO_1261_20 |
Popis: | Tubercular granulomas are a common manifestation of intraocular tuberculosis. These are said to be hypoxic granulomas with increased expression of vascular endothelial growth factor (VEGF). Management of these granulomas includes a combination of antitubercular therapy (ATT) and oral corticosteroids. We report a case of tubercular granuloma with exudative retinal detachment which was treated with weekly intravitreal anti-VEGF and antibiotic injections along with ATT and corticosteroids. The VEGF levels measured paralleled with the clinical regression of the granuloma. |
Databáze: | Directory of Open Access Journals |
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