Correlation of vascular endothelial growth factor with the clinical regression of tubercular granuloma

Autor: Manisha Agarwal, Chanda Gupta, K Varsha Mohan, Pramod K Upadhyay, Vivek Jha
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 68, Iss 9, Pp 2037-2040 (2020)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/ijo.IJO_1261_20
Popis: Tubercular granulomas are a common manifestation of intraocular tuberculosis. These are said to be hypoxic granulomas with increased expression of vascular endothelial growth factor (VEGF). Management of these granulomas includes a combination of antitubercular therapy (ATT) and oral corticosteroids. We report a case of tubercular granuloma with exudative retinal detachment which was treated with weekly intravitreal anti-VEGF and antibiotic injections along with ATT and corticosteroids. The VEGF levels measured paralleled with the clinical regression of the granuloma.
Databáze: Directory of Open Access Journals
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