| Autor: |
Cesar Molinos, Todd Sasser, Phil Salmon, Willy Gsell, David Viertl, James C. Massey, Krzysztof Mińczuk, Jie Li, Bijoy K. Kundu, Stuart Berr, Carlos Correcher, Ali Bahadur, Ali A. Attarwala, Simon Stark, Sven Junge, Uwe Himmelreich, John O. Prior, Kjell Laperre, Sonica Van Wyk, Michael Heidenreich |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Frontiers in Medicine, Vol 6 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2296-858X |
| DOI: |
10.3389/fmed.2019.00088 |
| Popis: |
Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing radiation. CT doses in pre-clinical in vivo imaging typically range from 50 to 1,000 mGy and biological effects in mice at this dose range have been previously described. [18F]FDG body doses in mice have been estimated to be in the range of 100 mGy for [18F]FDG. Yearly, the average whole body doses due to handling of activity by PET technologists are reported to be 3–8 mSv. A preclinical PET/CT system is presented with design features which make it suitable for small animal low-dose imaging. The CT subsystem uses a X-source power that is optimized for small animal imaging. The system design incorporates a spatial beam shaper coupled with a highly sensitive flat-panel detector and very fast acquisition ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
