Clinical features and outcome of stroke with COVID-19. COVID-19 Stroke Study Group (CSSG), India
Autor: | Rohit Bhatia, M V Padma Srivastava, P N Sylaja, Snigdha Komakula, Ashish Upadhyay, Vibhor Pardasani, Thomas Iype, Rajsrinivas Parthasarathy, Rajshekhar Reddy, Suman Kushwaha, Jayanta Roy, P Satish, Anjan Trikha, Naveet Wig, Lalit Dhar, Deepti Vibha, Venugopalan Y Vishnu, Awadh Kishore Pandit, Anu Gupta, A Elavarasi, Ayush Agarwal, Vipul Gupta, Rakesh K Singh, Harsh Oza, Hiral Halani, Dileep Ramachandran, Githin B George, Praveen Panicker, M K Suresh, S Kumaravelu, Dheeraj Khurana, Srijithesh P Rajendran, Vijaya Pamidimukkala, Salil Gupta, Jeyaraj D Pandian, Debashish Chowdhury, Nirendra K Rai, Arvind Sharma, Vivek K Nambiar |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Annals of Indian Academy of Neurology, Vol 24, Iss 5, Pp 668-685 (2021) |
Druh dokumentu: | article |
ISSN: | 0972-2327 1998-3549 |
DOI: | 10.4103/aian.AIAN_122_21 |
Popis: | Background and Purpose: Occurrence of stroke has been reported among patients with COVID-19. The present study compares clinical features and outcomes of stroke patients with and without COVID-19. Methods: The COVID-19 Stroke Study Group (CSSG) is a multicentric study in 18 sites across India to observe and compare the clinical characteristics of patients with stroke admitted during the current pandemic period and a similar epoch in 2019. The present study reports patients of stroke with and without COVID-19 (CoVS and non-CoVS, respectively) seen between February 2020 and July 2020. Demographic, clinical, treatment, and outcome details of patients were collected. Results: The mean age and gender were comparable between the two groups. CoVS patients had higher stroke severity and extent of cerebral involvement on imaging. In-hospital complications and death were higher among CoVS patients (53.06% vs. 17.51%; P < 0.001) and (42.31% vs. 7.6%; P < 0.001), respectively. At 3 months, higher mortality was observed among CoVS patients (67.65% vs. 13.43%; P < 0.001) and good outcome (modified Rankin score [mRS]: 0–2) was seen more often in non-CoVS patients (68.86% vs. 33.33%; P < 0.001). The presence of COVID-19 and baseline stroke severity were independent predictors of mortality. Conclusions: CoVS is associated with higher severity, poor outcome, and increased mortality. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and baseline stroke severity are independent predictors of mortality. |
Databáze: | Directory of Open Access Journals |
Externí odkaz: | |
Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |