| Autor: |
Florián Medina-Estévez, Manuel Zumbado, Octavio P. Luzardo, Ángel Rodríguez-Hernández, Luis D. Boada, Fernando Fernández-Fuertes, María Elvira Santandreu-Jimenez, Luis Alberto Henríquez-Hernández |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Toxics, Vol 8, Iss 3, p 66 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2305-6304 |
| DOI: |
10.3390/toxics8030066 |
| Popis: |
The role of inorganic elements as risk factors for stroke has been suggested. We designed a case-control study to explore the role of 45 inorganic elements as factors associated with stroke in 92 patients and 83 controls. Nineteen elements were detected in >80% of patients and 21 were detected in >80% of controls. Blood level of lead was significantly higher among patients (11.2 vs. 9.03 ng/mL) while gold and cerium were significantly higher among controls (0.013 vs. 0.007 ng/mL; and 18.0 vs. 15.0 ng/mL). Lead was associated with stroke in univariate and multivariate analysis (OR = 1.65 (95% CI, 1.09–2.50) and OR = 1.91 (95% CI, 1.20–3.04), respectively). Gold and cerium showed an inverse association with stroke in multivariate analysis (OR = 0.81 (95% CI, 0.69–0.95) and OR = 0.50 (95% CI, 0.31–0.78)). Future studies are needed to elucidate the potential sources of exposure and disclose the mechanisms of action. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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