The implications for advanced maternal age on pregnancy complications and adverse neonatal outcomes

Autor: Zeynep Gedik Özköse, Süleyman Cemil Oğlak
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Perinatal Journal, Vol 29, Iss 3, Pp 200-209 (2021)
Druh dokumentu: article
ISSN: 1305-3124
DOI: 10.2399/prn.21.0293005
Popis: Objective This study aimed to determine the effect of advanced maternal age (AMA) on maternal and neonatal outcomes in pregnant women aged ≥35 years compared with patients aged 30–34 years. Also, we aimed to analyze the risk estimates of potential confounders to identify whether these variables contributed to the development of adverse pregnancy outcomes or not. Methods This retrospective cohort study included 2284 pregnant women aged ≥35 years at the time of delivery who was delivered in a tertiary referral hospital from January 1, 2016, to December 31, 2020. We further classified these women into two subgroups: 35–39 years as early AMA (EAMA), and ≥40 years as very AMA (VAMA). Pregnancy complications and adverse neonatal outcomes were recorded. Results Compared to younger women, pregnant AMA women had significantly higher risks of complicated pregnancies, including a higher risk of gestational diabetes mellitus (GDM, p
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