Subclinical Hypothyroidism & Infertility: A Review

Autor: HS Ferdous, Faria Afsana, Nazmul Kabir Qureshi, Rushda SB Rouf, Irfan N Noor, AA Parvez, AS Mir
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: IMC Journal of Medical Science, Vol 8, Iss 1, Pp 17-24 (2014)
Druh dokumentu: article
ISSN: 2519-1721
2519-1586
Popis: Subclinical hypothyroidism (SCH) may be of greater clinical importance in women with “unexplained” infertility, especially when the luteal phase is inadequate, and such patients should be investigated for thyroid dysfunction in detail. To date, studies investigating the association between SCH and infertility are still based on the high serum thyroid stimulating hormone (TSH) levels while some older studies are based on the presence of an abnormal serum TSH after a thyrotropin releasing hormone (TRH) stimulation test. The recommendation in the current guidelines to treat subclinical hypothyroidism is based on minimal evidence and it is thought that with treatment the potential benefits outweigh the potential risks. Thyroxine-replacement therapy should be started in patients with SCH caused by conditions which are at high risk of progression to overt hypothyroidism. Ibrahim Med. Coll. J. 2014; 8(1): 17-24
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