Successful treatment of periodic disease and secondary AA amyloidosis in a colchicine-resistant patient

Autor:	V. V. Rameev, M. V. Bogdanova, L. V. Kozlovskaya, N. A. Mukhin
Jazyk:	ruština
Rok vydání:	2018
Předmět:	autoinflammation interleukin 1 pyrine inflammasome periodic disease mediterranean fever colchicine canakinumab amyloidosis aa Medicine
Zdroj:	Alʹmanah Kliničeskoj Mediciny, Vol 45, Iss 7, Pp 605-615 (2018)
Druh dokumentu:	article
ISSN:	2072-0505 2587-9294
DOI:	10.18786/2072-0505-2017-45-7-605-615
Popis:	The paper demonstrates current opportunities of effective management of periodic disease as an autoinflammatory disorder based on a clinical case of colchicine-resistant Mediterranean fever. We present modern approaches to the autoinflammation hypothesis and its molecular mechanisms in periodic disease. Based on literature and our own research results, we consider approaches to evaluate autoinflammation activity and to monitor treatment efficacy. Clinical value of S100A12, a novel marker of the activity of neutrophilic autoinflammation, is demonstrated.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8f066070345e46b0a2d23bf09f53f91d Zobrazit plný text záznamu View record in DOAJ