| Autor: |
Feby Dwi Wisudawati, Nove Hidajati, Faisal Fikri, Kuncoro Puguh Santoso, Amung Logam Saputro, Muhammad Thohawi Elziyad Purnama |
| Jazyk: |
English<br />Indonesian |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Veterinary Biomedical and Clinical Journal, Vol 5, Iss 1, Pp 19-24 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2622-1012 |
| DOI: |
10.21776/ub.VetBioClinJ.2023.005.01.3 |
| Popis: |
The purpose of this study was to determine the potential of administration robusta coffee extract as an antioxidant on the renal histopathology in mice exposed to monosodium glutamate (MSG) orally. This study used 20 adult male rats with Balb C strain divided into 5 experimental groups, namely K + (MSG 0.12 mg / head and Vitamin C 6 mg/mice), K- (MSG 0.12 mg/mice and Sodium carboxymethyl cellulose (CMC Na) 0,1 ml/mice), P1 (MSG 0.12 mg/mice and Robusta coffee extract 0.1 mg/mice), P2 (MSG 0.12 mg/mice and Robusta coffee extract 0.2 mg/mice), and P3 (MSG 0.12 mg/mice and 0.4 mg Robusta coffee extract mg/mice). The experimental group was treated every day at intervals between MSG and Vitamin C, CMC Na, and Robusta coffee extract for 60 min, the treatment was carried out for 42 days. Kidney histopathology scores were analyzed using the Saphiro-Wilk and Levene test to evaluate homogeneity, followed by the Kruskal Wallis test. The results of the Saphiro Wilk and Levene statistical analysis obtained p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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