Heart failure due to diastolic dysfunction of the left ventricle

Autor: Athanasios Gravos
Jazyk: Greek<br />English
Rok vydání: 2017
Předmět:
Zdroj: Epistīmonika Chronika, Vol 22, Iss Suppl. 1, Pp 125-133 (2017)
Druh dokumentu: article
ISSN: 1791-1362
2241-1666
Popis: Heart failure (HF) is a common cause of morbidity and mortality in elderly patients, and affects > 10% of patients aged > 70 years. HF is divided into HF with reduced ejection fraction and HF with preserved ejection fraction. HF with preserved ejection fraction is an entity that is often underestimated in everyday clinical practice, however, is a frequent cause of morbidity and dyspnea. Approximately 50% of patients with heart failure have preserved ejection fraction due to diastolic left ventricular dysfunction. Echocardiography is the gold standard test for the diagnosis. Biomarkers such as natriuretic peptides have auxiliary role and are not superior to echocardiography for the diagnosis, as they have low sensitivity and predictive value. For early diagnosis is required consideration and combination of clinical and echocardiographic findings, while the combined use of echocardiography and biomarkers contribute to early diagnosis. The main echocardiographic findings suggestive of diastolic dysfunction are left ventricular hypertrophy and dilation of the left atrium. The role of echocardiography is essential for diagnosis, differential diagnosis, determining the severity and prognosis and monitoring the response to therapeutic interventions. The prognosis of the disease remains unfavorable and no therapeutic intervention does currently reduce mortality, unlike heart failure with reduced ejection fraction, where a number of pharmaceutical and non- pharmaceutical interventions lead to reduction in morbidity and mortality. The goal of treatment is the detection and treatment of risk factors and co-morbidities and alleviation of the patient's symptoms.
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