Effect of recipient-donor sex and weight mismatch on graft survival after deceased donor renal transplantation.

Autor:	Frank-Peter Tillmann, Ivo Quack, Magdalena Woznowski, Lars Christian Rump
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Medicine Science
Zdroj:	PLoS ONE, Vol 14, Iss 3, p e0214048 (2019)
Druh dokumentu:	article
ISSN:	1932-6203
DOI:	10.1371/journal.pone.0214048
Popis:	This study evaluated the combined effect of recipient-to-donor weight and sex mismatch after deceased-donor renal transplantation in a German transplant cohort and the evolution of recipient-to-donor weight difference over a 13-year observation period. The association of absolute weight and sex difference with graft failure was explored in an outpatient cohort of deceased-donor transplant recipients who underwent kidney transplantation between 2000 and 2012. Graft failure was defined as repeated need for dialysis or death with a functioning graft. Recipient and donor sex pairings were classified as sex concordant (MDMR/FDFR) or discordant (MDFR/FDMR). These classes were further stratified into four groups according to recipient-to-donor weight mismatch ≥10 kg (recipient > donor) or
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