How splicing confers treatment resistance in prostate cancer

Autor:	Prathyusha Konda, Srinivas R Viswanathan
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	AR-V7 prostate cancer nuclear import intranuclear mobility transcriptional activity androgen receptor Medicine Science Biology (General) QH301-705.5
Zdroj:	eLife, Vol 11 (2022)
Druh dokumentu:	article
ISSN:	2050-084X
DOI:	10.7554/eLife.82070
Popis:	A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e8bdecead21340bbb6a6fe8073da6ab9 Zobrazit plný text záznamu View record in DOAJ