Allergic bronchopulmonary candidiasis: A review of the literature and a case report

Autor: Martin Scurek, Eva Pokojova, Martina Doubkova, Kristian Brat
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-6 (2022)
Druh dokumentu: article
ISSN: 1471-2466
DOI: 10.1186/s12890-022-01921-3
Popis: Abstract Background Allergic bronchopulmonary candidiasis (ABPC) is an uncommon clinical syndrome associated with immune hypersensitivity to Candida species. Case presentation The case presentation describes a 58-year-old man with acute respiratory failure and bilateral lung infiltrates. Due to high inflammatory markers and a chest X-ray indicating lung infiltration, he was initially treated for pneumonia with combined antibiotics. Despite comprehensive treatment at the ICU, the patient’s clinical status deteriorated rapidly, and further investigations provided a rare diagnosis of ABPC. After several days of combined corticosteroid and antifungal therapy, we observed rapid clinical improvement and subsequent resolution of the pulmonary infiltrates. Conclusion This case report presented a rare case of ABPC mimicking bilateral pneumonia and acute respiratory failure. Our case highlighted the importance of prompt corticosteroid and antifungal treatment initiation as it resulted in rapid clinical improvement and a near complete reversal of the bilateral lung infiltrates.
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